|Project Summary||Project Information|
Academic cell culture is primarily performed on two-dimensional plastic surfaces and kept under static conditions. Static, 2-D cell cultures are not representative of the cells’ environment in-vivo since they depend on chemical conditions only. The main goal for this project is to develop a culture chamber that allows in-vitro research to more closely resemble in-vivo conditions by providing chemical and mechanical stimulation. The culture chamber should maintain sterile, standard culture conditions (5% CO2, 37 degrees Celsuis), while applying tensile strain on cultured cells. The culture chamber should fit generic, EVOS, and Leica microscopes for viewing cells, and it should be safe and intuitive for use with an undergraduate student population.
VISTING FROM IMAGINE? CHECK OUT OUR IMAGINE LINK HERE.
|Amanda Castagnino||Biomedical Engineer, EDGE Facilitator||axc9355|
|Natalie Nold||Biomedical Engineer, Project Manager||nmn5966|
|Emily Wood||Mechanical Engineer, Software Expert, Treasurer||enw4374|
|Emily Adams||Mechanical Engineer, Team Facilitator||exa4926|
|Simran Singh||Biomedical Engineer, Cell Culture Expert, Notetaker||sxs2843|
Work Breakdown: By Phase
|MSD I & II||MSD I||MSD II|
Work Breakdown: By Topic
|Project Management||Design Tools||Design Documentation||Implementation||Validation||Presentation & Dissemination|
AcknowledgementsSpecial thanks for Michael Zona, Jennifer Bailey, and the RIT Biomedical Engineering Department.
Thanks to ASTM International for additional funding.
Additional thanks for Michelle Horan, Dr. Blanca Lapizco-Encinas & Lab, Gary Hodenius, Dr. Vinay Abhyankar, Dr. Steven Day, Professor William Humphrey, Daniel Zinobile, Dr. Thomas Smith, the RIT Machine Shop, and the RIT Construct.