P18083: Micropipette Tip Box Filler
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Preliminary Detailed Design

Table of Contents

Team Vision for Preliminary Detailed Design Phase

Team Vision

Team Vision

Feasibility: Prototyping, Analysis, Simulation

Storage

In order to estimate the required critical angle to get the tips start sliding on the storage ramp we made few assumptions. Assuming the tips are cylindrical shaped plastic and that it slides without slipping we can apply a simple friction equation to estimate the slider angle. These assumptions allow us to get a minimal angle since the tips will have less friction The angle calculated was 45 deg.

Sorter

The construction below was used to test the feasibility of the blockade sorter design. Pipette tips were dropped at the top in different orientations and amounts with the device at a 45 degree angle.
Sorter Test

Sorter Test

Sorter Test

Sorter Test

After performing this test we are confident in the feasibility of this sorter design. However occasionally a tip would get stuck and the top and would need to shaken free. Further testing is planned at different angles, drop heights, and shaker configurations to determine the necessity of shaker motors.

Rails

Prototype lanes were made on aluminium on different thicknesses and different sized lanes. Below are videos on how the pipettes roll down them. We can see that the pipettes do not slide down smoothly due to the following reasons.

• The small extrusions on the pipettes makes it difficult to slide down when the lane diameter is too small. The minimum diameter had to be above 0.250”.

various lane widths with pipettes(from left to right - 0.271 inches, 0.250 inches with a chamfer, 0.180

various lane widths with pipettes(from left to right - 0.271 inches, 0.250 inches with a chamfer, 0.180

• When the material is too thick it makes it makes the pipettes difficult to slide down, therefore a chamfer had to be added on one side of the plate. The chamfers could not be added when the lanes were very close. We had to consider having alternate lanes.

0.250 inches with chamfer

0.250 inches with chamfer

0.270 inches without chamfer

0.270 inches without chamfer

• The diameter of the lanes changes due to the long nature of the lanes as they are getting bent.

multiple lanes prototype

multiple lanes prototype

• The pipettes can’t be filled by just sliding the tip box under it as the tips can’t be easily aligned with the box.

Due to these problems the team has decided to use rods instead of plates giving an ease of manufacture and also gives better results when pipettes slide down.

Drawings, Schematics, Flow Charts, Simulations

storage

storage

drawings

drawings

Sorter Drawing

Sorter Drawing

Sorter Cover Drawing

Sorter Cover Drawing

Asembly for pipette flow

Asembly for pipette flow

Bill of Material (BOM)

Bill Of Material

Bill Of Material

Risk Assessment

Risk Assessment

Risk Assessment

Plans for next phase

Plans for next phase

Plans for next phase

Individual Three Week Plans:

Andrew Mashayekhi

Abdallah Hassanein Individual Phase Plan

Parikshit Linga


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